The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 2021
Filed:
Dec. 31, 2015
Wisconsin Alumni Research Foundation, Madison, WI (US);
James A. Thomson, Madison, WI (US);
William L. Murphy, Waunakee, WI (US);
Charles D. Page, Sun Prairie, WI (US);
Michael P. Schwartz, Madison, WI (US);
Zhonggang Hou, Madison, WI (US);
WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (US);
Abstract
The present invention relates to three-dimensional (3D) tissue constructs and methods of using such 3D tissue constructs to screen for neurotoxic agents. In particular, provided herein are methods of producing and using complex, highly uniform human tissue models comprising physiologically relevant human cells, where the tissue models have the degree of sample uniformity and reproducibility required for use in quantitative high-throughput screening applications.