The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2021

Filed:

Jan. 08, 2019
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Dirk E. Smith, Bainbridge Island, WA (US);

Ian Foltz, Burnaby, CA;

Chadwick T. King, North Vancouver, CA;

Ai Ching Lim, Mercer Island, WA (US);

Rutilio Clark, Bainbridge Island, WA (US);

Michael R. Comeau, Bainbridge, WA (US);

Randal R. Ketchem, Snohomish, WA (US);

Donghui Shi, Thousand Oaks, CA (US);

Xiaoshan Min, Burlingame, CA (US);

Zhulun Wang, Palo Alto, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/24 (2006.01); A61K 39/00 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); C07K 16/244 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C12N 15/11 (2013.01);
Abstract

Described herein are compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies. In particular embodiments, the disclosure provides fully human anti-ST2 antibodies and derivatives and variants thereof. Further provided are nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives. Also, provided are methods of making and using such antibodies including methods of treating and preventing autoimmune and inflammatory disorders.


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