The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2021

Filed:

Jan. 30, 2019
Applicant:

Flagship Pioneering Innovations V, Inc., Cambridge, MA (US);

Inventors:

Avak Kahvejian, Lexington, MA (US);

Jordi Mata-Fink, Baltimore, MD (US);

Jonathan Barry Hurov, Bedford, MA (US);

Chengyi Jenny Shu, Cambridge, MA (US);

George Huck Neubauer, Malden, MA (US);

Julian Alexander Stanley, Oregon City, OR (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); A61P 37/06 (2006.01); A61K 9/00 (2006.01); A61P 17/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61P 17/06 (2018.01); A61P 37/06 (2018.01);
Abstract

The present invention provides methods for treating inflammatory or autoimmune disease using mGluR8 activators, such as mGluR8 activating antibodies, among others. The invention also features compositions containing mGluR8 activators, methods of diagnosing patients with mGluR8-associated inflammatory or autoimmune disease, and methods of predicting the response of an inflammatory or autoimmune disease or condition in a subject to treatment with mGluR8 activators.


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