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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11059879 B1

PDFFull Text
Expired
Date of Patent:
Jul. 13, 2021

Filed:

Oct. 27, 2016

Chimeric antigen receptor molecules and uses thereof

Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Radhika Thokala, Houston, TX (US);

Laurence J.N. Cooper, Houston, TX (US);

Simon Olivares, Houston, TX (US);

Assignee:

BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);

Attorney:

Parker Highlander PLLC

Primary Examiner:

Peter J Reddig

Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 39/44 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61P 35/02 (2006.01); A61P 35/00 (2006.01); C07K 14/725 (2006.01); C07K 16/28 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70517 (2013.01); A61K 39/00 (2013.01); A61K 39/39558 (2013.01); A61K 39/44 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 16/2866 (2013.01); A61K 38/00 (2013.01); A61K 2039/507 (2013.01); A61K 2039/5158 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01);
Abstract

Chimeric antigen receptor (CAR) polypeptides are provided comprising an antigen binding domain; a hinge domain; a transmembrane domain and an intracellular signaling domain, wherein the CAR polypeptide binds to a target antigen and wherein the antigen binding domain comprises HCDR sequences from a first antibody that binds to the target antigen and LCDR sequences from a second antibody that binds to the target antigen. In certain aspects, the target antigen is CD123.

Find Patent Forward Citations

Thokala, Radhika. (2021). Chimeric antigen receptor molecules and uses thereof (U.S. Patent No. 11059879). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11059879

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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