The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 2021
Filed:
Mar. 15, 2019
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Ali Shilatifard, Chicago, IL (US);
Lu Wang, Chicago, IL (US);
Assignee:
Northwestern University, Evanston, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/575 (2006.01); C07K 14/47 (2006.01); C07K 7/06 (2006.01); C07K 16/30 (2006.01); A61K 38/22 (2006.01); C12Q 1/6886 (2018.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C07K 14/5759 (2013.01); A61K 38/2264 (2013.01); C07K 7/06 (2013.01); C07K 14/4702 (2013.01); C07K 16/3015 (2013.01); C12N 15/1137 (2013.01); C12Q 1/6886 (2013.01); C12Y 201/01043 (2013.01); C12N 2310/14 (2013.01); C12N 2310/20 (2017.05); C12N 2310/531 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract
Disclosed are methods for treating Set1/COMPASS-associated cancers characterized by expression of Set1B/COMPASS. The methods typically include administering a therapeutic amount of an inhibitor of the Set1B/COMPASS pathway and/or an agonist for a target that is negatively regulated by the Set1B/COMPASS pathway.