logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11059795 B1

PDFFull Text
Date of Patent:
Jul. 13, 2021

Filed:

Apr. 20, 2020

Androgen receptor modulators and methods for their use

Applicants:

Essa Pharma, Inc., Vancouver, CA;

The University of British Columbia, Vancouver, CA;

Provincial Health Services Authority, Vancouver, CA;

Inventors:

Han-Jie Zhou, Foster City, CA (US);

Peter Virsik, Portola Valley, CA (US);

Raymond John Andersen, Vancouver, CA;

Marianne Dorothy Sadar, West Vancouver, CA;

Assignees:

ESSA Pharma, Inc., Vancouver, CA;

The University of British Columbia, Vancouver, CA;

Provincial Health Services Authority, Vancouver, CA;

Attorney:

Cooley LLP

Primary Examiner:

Paul V Ward

Int. Cl.
CPC ...
C07D 263/46 (2006.01); A61P 35/00 (2006.01); C07D 271/113 (2006.01); C07D 261/08 (2006.01); C07D 263/48 (2006.01); C07D 231/38 (2006.01); C07D 239/42 (2006.01); C07D 233/74 (2006.01); C07D 277/36 (2006.01); C07D 277/42 (2006.01); C07D 277/56 (2006.01); C07D 307/64 (2006.01); C07D 241/20 (2006.01); C07D 263/38 (2006.01); C07D 233/84 (2006.01); C07D 233/88 (2006.01); C07D 233/80 (2006.01); C07D 233/76 (2006.01);
U.S. Cl.
CPC ...
C07D 263/46 (2013.01); A61P 35/00 (2018.01); C07D 231/38 (2013.01); C07D 233/74 (2013.01); C07D 233/76 (2013.01); C07D 233/80 (2013.01); C07D 233/84 (2013.01); C07D 233/88 (2013.01); C07D 239/42 (2013.01); C07D 241/20 (2013.01); C07D 261/08 (2013.01); C07D 263/38 (2013.01); C07D 263/48 (2013.01); C07D 271/113 (2013.01); C07D 277/36 (2013.01); C07D 277/42 (2013.01); C07D 277/56 (2013.01); C07D 307/64 (2013.01);
Abstract

The present invention relates to compounds of formula (I)-(VI) and/or (A)-(H-I), or any subgenera thereof, or a pharmaceutically acceptable salt, tautomer or stereoisomer. The compounds of the present disclosure are useful in modulating androgen receptor activity and for treating cancer including prostate cancer.

Find Patent Forward Citations

Loading…