The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2021

Filed:

Sep. 07, 2018
Applicants:

Institute of Mataria Medica, Chinese Academy of Medical Sciences, Bejing, CN;

Shijiazhuang Yiling Pharmaceutical Co., Ltd., Shijiazhuang, CN;

Inventors:

Yang Lv, Shijiazhuang, CN;

Shiying Yang, Shijiazhuang, CN;

Gengtao Liu, Shijiazhuang, CN;

Dan Zhang, Shijiazhuang, CN;

Xiuqi Bao, Shijiazhuang, CN;

Ping Xie, Shijiazhuang, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 235/34 (2006.01);
U.S. Cl.
CPC ...
C07C 235/34 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention discloses a type-B crystal form of fenolamine, a preparation method thereof, and a composition and use thereof, more particularly a type-B crystal form of the fenolamine compound (chemical name: trans-2-(2,5-dimethoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-N-(4-hydroxyphenylethyl)acrylamide, a preparation method thereof, and a composition and use thereof. Specifically, the present invention discloses the presence of a solid of a type-B fenolamine crystal form in solid state; a method for preparing the solid of type-B crystal form; and use of the solid of the type-B fenolamine crystal form as a pharmaceutical active ingredient in the manufacture of a medicament for prevention and treatment of Parkinson's disease (PD), improvement of learning and memory disorder, and treatment of memory loss and Alzheimer's disease (AD).


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