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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11058768 B1

PDFFull Text
Date of Patent:
Jul. 13, 2021

Filed:

Apr. 16, 2015

Stable protein formulations comprising a molar excess of sorbitol

Applicants:

Biocon Ltd., Bangalore, IN;

Mylan Gmbh, Zurich, CH;

Inventors:

Kala Chandramouli, Bangalore, IN;

Rohan Pai, Nipani, IN;

Assignees:

BIOCON LTD.;

MYLAN GMBH;

Attorneys:

Marianne Fuierer

Olive Law Group, PLLC

Primary Examiner:

Laura B Goddard

Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/32 (2006.01); A61K 9/19 (2006.01); A61K 47/26 (2006.01); A61K 47/10 (2017.01); A61K 47/20 (2006.01); A61J 1/20 (2006.01); A61J 1/06 (2006.01); A61J 1/14 (2006.01); A61K 47/18 (2017.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39591 (2013.01); A61J 1/06 (2013.01); A61J 1/1412 (2013.01); A61J 1/2006 (2015.05); A61K 9/19 (2013.01); A61K 47/10 (2013.01); A61K 47/183 (2013.01); A61K 47/20 (2013.01); A61K 47/26 (2013.01); C07K 16/32 (2013.01); A61K 9/0019 (2013.01); C07K 2317/24 (2013.01);
Abstract

A stable pharmaceutical formulation comprising a protein of interest, sorbitol and polyethylene glycol (PEG). The sorbitol and protein is present in a molar ratio of 550 to 700 mole of sorbitol:1 mole of protein and the PEG to protein is present in the molar ratio of 2-50:1. The formulation optionally comprising buffer. The formulation in lyophilised form is stable for at least 4 years at 2-8° C. Also provided is a process for preparing the composition and a pharmaceutical kit comprising the same.

Find Patent Forward Citations

Chandramouli, Kala. (2021). Stable protein formulations comprising a molar excess of sorbitol (U.S. Patent No. 11058768). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11058768

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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