The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 2021
Filed:
Nov. 25, 2020
Applicant:
King Abdulaziz University, Jeddah, SA;
Inventors:
Hibah M. Aldawsari, Jeddah, SA;
Shaimaa M. Badr-Eldin, Jeddah, SA;
Nourah Y. Assiri, Jeddah, SA;
Abdelsattar Omar, Jeddah, SA;
Assignee:
King Abdulaziz University, Jeddah, SA;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 31/475 (2006.01); A61K 31/4375 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1273 (2013.01); A61K 9/0043 (2013.01); A61K 31/475 (2013.01);
Abstract
Emulsome compositions comprising phosphatidylcholine, cholesterol, tristearin, and one or more lipophilic bioactive agents such as vinpocetine are provided. The emulsomes may further comprise surface modifications of either [N-(carbonyl-methoxypropylethyleneglycol-2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt] (MPEG-DSPE) for peglyation or stearylamine for cationization. Methods of improving brain delivery of lipophilic bioactive agents by intranasally administering such emulsome compositions are also provided.