The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 2021

Filed:

Dec. 30, 2016
Applicant:

Quest Diagnostics Investments Llc, Madison, NJ (US);

Inventors:

Shih-Min Cheng, San Juan Capistrano, CA (US);

Joseph J. Catanese, San Juan Capistrano, CA (US);

Andrew Grupe, San Juan Capistrano, CA (US);

Feras Hantash, Mission Viejo, CA (US);

Frederic M. Waldman, San Juan Capistrano, CA (US);

Kevin Qu, San Juan Capistrano, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6874 (2018.01); C12Q 1/6886 (2018.01); C12Q 1/6869 (2018.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12N 15/1068 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01);
Abstract

The present technology relates to methods for determining whether a patient having thyroid nodules with indeterminate cytology will benefit from diagnostic surgery, e.g., lobectomy. These methods are based on screening a patient's thyroid nodules and detecting alterations in target nucleic acid sequences corresponding to a specific set of thyroid cancer-related genes. Kits for use in practicing the methods are also provided.


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