The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 2021

Filed:

Dec. 05, 2017
Applicant:

Stichting Katholieke Universiteit, Nijmegen, NL;

Inventors:

Paul Kouwer, Nijmegen, NL;

Alan Edward Rowan, Nijmegen, NL;

Daniël Schoenmakers, Nijmegen, NL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08G 61/04 (2006.01); A61L 27/52 (2006.01); C08G 65/333 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C08G 61/04 (2013.01); A61L 27/52 (2013.01); C08G 65/33324 (2013.01); C12N 5/0068 (2013.01); C08G 2261/122 (2013.01); C08G 2261/135 (2013.01); C08G 2261/1424 (2013.01); C08G 2261/1432 (2013.01); C08G 2261/332 (2013.01); C08G 2261/76 (2013.01); C12N 2533/20 (2013.01); C12N 2533/30 (2013.01); C12N 2533/76 (2013.01); C12N 2537/10 (2013.01);
Abstract

A polymer hydrogel having a polymer formed by the crosslinking reaction of a polymeric unit A according to formula (I), with a crosslinking unit B according to formula (II) and water, wherein n=100-10,000, preferable 250-2500, more preferable 500-1500; m=independently 2-10, preferably 3 or 4; FG is a functional moiety that can be covalently coupled to the complementary functional moiety F1 or F2 of the crosslinking unit (B); k=0.01-0.05; h=0, 1 or 2; the spacer is an organic moiety, having a main chain comprising at least two functional moieties F1 and F2, wherein the length of the crosslinker in the extended conformation as determined by molecular modeling (including spacer and functional groups F1 and F2) is between 2.5 and 12 nm, or wherein the length is between 20 and 80 atoms.


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