The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 06, 2021
Filed:
Feb. 19, 2015
Applicant:
University of Florida Research Foundation, Inc., Gainesville, FL (US);
Inventors:
Cristhian J. Ildefonso, Gainesville, FL (US);
Alfred S. Lewin, Gainesville, FL (US);
Qiuhong Li, Gainesville, FL (US);
Assignee:
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 38/17 (2006.01); A61K 9/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); A61K 9/0048 (2013.01); A61K 38/1709 (2013.01); A61K 48/0075 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/10 (2013.01); C07K 2319/50 (2013.01);
Abstract
The present invention provides methods and compositions for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration, ocular neovascularization, or inflammation, including ocular inflammation. In some embodiments, the methods comprise administering an expression vector that delivers a secretable and cell penetrating Nrf2 to a subject in need thereof.