The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 2021

Filed:

Feb. 23, 2018
Applicant:

Qilu Antibiotics Pharmaceutical Co. Ltd., Jinan, CN;

Inventors:

Chuanshan Hou, Jinan, CN;

Fei Tang, Jinan, CN;

Meiju Fan, Jinan, CN;

Xin Wang, Jinan, CN;

Jinglong Fu, Jinan, CN;

Michao Shi, Jinan, CN;

Xi Lei, Jinan, CN;

Hongmei Xu, Jinan, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 501/34 (2006.01);
U.S. Cl.
CPC ...
C07D 501/34 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to a crystal of cephalosporin intermediate 7α-methoxy cephalothin (I) and a method for preparing same. The crystal of 7α-methoxy cephalothin (I) undergoes Cu-Ka radiation and X-ray powder diffraction expressed in terms of angle 2θ; the crystal of 7α-methoxy cephalothin (I) has characteristic absorption peaks at positions of 7.34°±0.20°, 12.71°±0.20°, 14.25°±0.20°, 14.68°±0.20°, 16.52°±0.20°, 17.99°±0.20°, 19.98°±0.20°, and 22.69°±0.20°. The crystal of 7α-methoxy cephalothin provided by the present invention is easy to prepare. Related test data shows that the crystal of 7α-methoxy cephalothin has high purity, low impurity content, and good stability. The preparation cost is low, the preparation method is simple to operate, conditions are mild and easy to control, and crystals of 7α-methoxy cephalothin can be obtained stably. The invention is applicable to industrial production.


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