The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 06, 2021
Filed:
Jun. 25, 2019
Bristol-myers Squibb Company, Princeton, NJ (US);
Andrew K. Dilger, Ewing, NJ (US);
James R. Corte, Yardley, PA (US);
Indawati De Lucca, Pennington, NJ (US);
Tianan Fang, Newtown, PA (US);
Wu Yang, Princeton Junction, NJ (US);
Yufeng Wang, Belle Mead, NJ (US);
Kumar Balashanmuga Pabbisetty, Piscataway, NJ (US);
William R. Ewing, Yardley, PA (US);
Yeheng Zhu, Stockton, NJ (US);
Ruth R. Wexler, Belle Mead, NJ (US);
Donald J. P. Pinto, Churchville, PA (US);
Michael J. Orwat, New Hope, PA (US);
Leon M. Smith, II, Somerset, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention provides compounds of Formula (1): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.