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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11053212 B1

PDFFull Text
Expired
Date of Patent:
Jul. 06, 2021

Filed:

Aug. 22, 2019

Benzimidazole derivatives as bromodomain inhibitors

Applicant:

Glaxosmithkline Intellectual Property Development Limited, Middlesex, GB;

Inventors:

Rino Antonio Bit, Stevenage, GB;

John Alexander Brown, Stevenage, GB;

Philip G. Humphreys, Stevenage, GB;

Katherine Louise Jones, Stevenage, GB;

Assignee:

GlaxoSmithKline Intellectual Property Development Limited, Middlesex, GB;

Attorneys:

James K. Leonard

Nicole Ginanni

Primary Examiner:

John S Kenyon

Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); A61P 29/00 (2006.01); A61P 37/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07B 2200/13 (2013.01);
Abstract

Compounds of formula (I) and salts thereof: wherein R, R, R, Rare defined herein. Compounds of formula (I) and salts thereof have been found to inhibit the binding of the BET family of bromodomain proteins to, for example, acetylated lysine residues and thus may have use in therapy, for example in the treatment of autoimmune and inflammatory diseases, such as rheumatoid arthritis; and cancers.

Find Patent Forward Citations

Bit, Rino. (2021). Benzimidazole derivatives as bromodomain inhibitors (U.S. Patent No. 11053212). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11053212

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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