The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 2021

Filed:

Jan. 25, 2019
Applicant:

The Texas A&m University Sytem, College Station, TX (US);

Inventors:

Arum Han, College Station, TX (US);

Song-I Han, College Station, TX (US);

Assignee:

THE TEXAS A&M UNIVERSITY SYSTEM, College Station, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B03C 5/02 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
B03C 5/026 (2013.01); B01L 3/502784 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0809 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0424 (2013.01); B03C 2201/18 (2013.01);
Abstract

A dielectrophoresis-based in-droplet cell concentrator is disclosed herein. The concentrator can include a concentration microchannel having an input port and two or more outlet ports. The input port introduces cell-encapsulated droplets or particle-encapsulated droplets into the microchannel; a first outlet port receives droplets including most of the cells or particles and a second output port receives droplets including few cells or particles. The concentrator also can include a pair of electrodes. When voltage is applied, the electrodes will create an electric field across the microchannel. The concentrator adds new capabilities to droplet microfluidics operations, such as adjusting concentrations of cells in droplets, separating cells of different properties from inside droplets, and solution exchange.


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