The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 06, 2021
Filed:
Jan. 31, 2019
Applicant:
Avelas Biosciences, Inc., La Jolla, CA (US);
Inventors:
Jesus Gonzalez, Carlsbad, CA (US);
Junjie Liu, San Diego, CA (US);
Assignee:
Avelas Biosciences, Inc., La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 49/14 (2006.01); A61K 47/60 (2017.01); A61K 47/64 (2017.01); A61K 47/65 (2017.01);
U.S. Cl.
CPC ...
A61K 49/0056 (2013.01); A61K 47/60 (2017.08); A61K 47/64 (2017.08); A61K 47/65 (2017.08); A61K 49/0032 (2013.01); A61K 49/0054 (2013.01);
Abstract
Disclosed herein is a selective delivery molecule comprising: (a) an acidic sequence (portion A) which is effective to inhibit or prevent the uptake into cells or tissue retention, (b) a molecular transport or tissue retention sequence (portion B), and (c) a linker between portion A and portion B, and (d) cargo moieties (portion Dand D).