The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 06, 2021
Filed:
Nov. 13, 2017
Applicant:
Tokyo University of Science Foundation, Tokyo, JP;
Inventors:
Etsuko Miyamoto, Tokyo, JP;
Masaaki Ozawa, Tokyo, JP;
Assignee:
Tokyo University of Science Foundation, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); A61P 35/00 (2006.01); A61K 38/05 (2006.01);
U.S. Cl.
CPC ...
A61K 47/545 (2017.08); A61K 38/05 (2013.01); A61P 35/00 (2018.01);
Abstract
A Ras protein degradation inducing molecule that can induce degradation of Ras proteins, and a pharmaceutical composition that contains this Ras protein degradation inducing molecule are provided. The Ras protein degradation inducing molecule is a conjugate of a Ras protein affinity molecule which has affinity to Ras proteins, and a proteolysis-inducing tag which has affinity to protease and does not inhibit proteolysis of proteins by the protease.