The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 2021

Filed:

May. 15, 2018
Applicants:

Janssen Vaccines & Prevention B.v., Leiden, NL;

Bavarian Nordic A/s, Kvistgaard, DK;

Inventors:

Ahmad Shakeb Sediq, Basel, CH;

Wouter Frank Tonnis, Berlin, DE;

Martinus Anne Hobbe Capelle, Sassenheim, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/12 (2006.01); C12N 15/86 (2006.01); C12N 7/00 (2006.01); A61K 39/275 (2006.01); A61K 39/285 (2006.01); A61P 31/04 (2006.01); A61K 47/20 (2006.01);
U.S. Cl.
CPC ...
A61K 39/285 (2013.01); A61K 47/20 (2013.01); A61P 31/04 (2018.01);
Abstract

Described herein are compositions and pharmaceutical compositions including poxviruses, in particular vaccinia virus such as modified vaccinia Ankara (MVA) virus, a sulfate salt at a concentration between about 5 mM and 300 mM and a buffer, wherein the composition has a pH of between about 6.0 and 8.5. Also described are methods for stabilizing a poxvirus composition by preparing said viral formulation.


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