The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 2021

Filed:

Oct. 22, 2019
Applicant:

Epizyme, Inc., Cambridge, MA (US);

Inventors:

Kevin W. Kuntz, Woburn, MA (US);

Richard Chesworth, Concord, MA (US);

Kenneth W. Duncan, Westwood, MA (US);

Heike Keilhack, Belmont, MA (US);

Natalie Warholic, Cambridge, MA (US);

Christine Klaus, Waban, MA (US);

Sarah K. Knutson, Lincoln, MA (US);

Timothy J. N. Wigle, Waltham, MA (US);

Masashi Seki, Tsukuba, JP;

Syuji Shirotori, Tsukuba, JP;

Satoshi Kawano, Tsukuba, JP;

Assignee:

Epizyme, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/444 (2006.01); A61K 31/506 (2006.01); A61K 31/4412 (2006.01); A61K 31/553 (2006.01); A61K 31/551 (2006.01); C07D 213/64 (2006.01); C07D 409/12 (2006.01); C07D 498/08 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 491/08 (2006.01); C07D 491/107 (2006.01); C07D 405/14 (2006.01); A61K 31/443 (2006.01); A61K 31/4433 (2006.01); A61K 31/4436 (2006.01); A61K 31/4439 (2006.01); A61K 31/4545 (2006.01); A61K 31/4709 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/443 (2013.01); A61K 31/444 (2013.01); A61K 31/4412 (2013.01); A61K 31/4433 (2013.01); A61K 31/4436 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/551 (2013.01); A61K 31/553 (2013.01); C07D 213/64 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 491/08 (2013.01); C07D 491/107 (2013.01); C07D 498/08 (2013.01);
Abstract

The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.


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