The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 06, 2021
Filed:
Dec. 12, 2019
Kaohsiung Medical University, Kaohsiung, TW;
Yeh-Long Chen, Kaohsiung, TW;
Tian-Lu Cheng, Kaohsiung, TW;
Cherng-Chyi Tzeng, Kaohsiung, TW;
Chih-Hua Tseng, Kaohsiung, TW;
Ta-Chun Cheng, Kaohsiung, TW;
Kai-Wen Cheng, Kaohsiung, TW;
Wei-Fen Luo, Kaohsiung, TW;
KAOHSIUNG MEDICAL UNIVERSITY, Kaohsiung, TW;
Abstract
The present invention provides novel pyrazolo[4,3-c]quinoline derivatives exhibiting specifically inhibition activity to microbiota β-glucuronidase, whereby providing potent activities to prevent chemotherapy-induced diarrhea (CID) of cancers. Therefore, the compounds of the present invention can be used as (1) chemotherapy-adjuvant to prevent chemotherapy-induced diarrhea (CID) and enhance chemotherapeutic efficiency of cancers; (2) health-food supplement to prevent the carcinogens induced colon carcinoma.