The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 06, 2021
Filed:
Apr. 24, 2019
Evonik Operations Gmbh, Essen, DE;
Roland Brock, Kalkar, DE;
Rike Nabbefeld, Cologne, DE;
Silko Grimm, Rossdorf, DE;
Anne Benedikt, Frankfurt, DE;
Andrea Engel, Birmingham, AL (US);
Alexander Henrik Baron van Asbeck, Nijmegen, NL;
Jürgen Dieker, Zutphen, NL;
Evonik Operations GmbH, Essen, DE;
Abstract
A nanoparticle includes a core. The core includes a bio-resorbable polyester and a hydrophilic polymer. The hydrophilic polymer is a portion of the bio-resorbable polyester or a separate polymer. An acylated human lactoferrin-derived peptide is coated onto the core. The acylated human lactoferrin-derived peptide is a peptide with the amino acid sequence SEQ ID NO. 1: KCFQWQRNMRKVRGPPVSCIKR or an amino acid sequence, which does not differ by more than 8 amino acid positions from the sequence SEQ ID NO: 1. The N-terminus of the human lactoferrin-derived peptide is acylated with a C-monoacyl group.