The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2021
Filed:
Oct. 17, 2014
Applicant:
Seven Bridges Genomics Inc., Charlestown, MA (US);
Inventor:
Deniz Kural, Somerville, MA (US);
Assignee:
Seven Bridges Genomics Inc., Charlestown, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 30/00 (2019.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
G16B 30/00 (2019.02); C12Q 1/6869 (2013.01); C12Q 2535/122 (2013.01); C12Q 2537/165 (2013.01);
Abstract
The invention includes methods for aligning reads (e.g., nucleic acid reads) comprising repeating sequences, methods for building reference sequence constructs comprising repeating sequences, and systems that can be used to align reads comprising repeating sequences. The method is scalable, and can be used to align millions of reads to a construct thousands of bases long. The methods and systems can additionally account for variability within a repeating sequence, or near to a repeating sequence, due to genetic mutation.