The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2021

Filed:

Feb. 08, 2018
Applicant:

Purdue Research Foundation, West Lafayette, IN (US);

Inventors:

Robert Graham Cooks, West Lafayette, IN (US);

Livia Schiavinato Eberlin, Lafayette, IN (US);

Christina Ramires Ferreira, West Lafayette, IN (US);

Allison Lisa Dill, Indianapolis, IN (US);

Demian R. Ifa, West Lafayette, IN (US);

Assignee:

Purdue Research Foundation, West Lafayette, IN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); G01N 33/92 (2006.01); H01J 49/00 (2006.01); H01J 49/16 (2006.01); H01J 49/14 (2006.01);
U.S. Cl.
CPC ...
G01N 33/92 (2013.01); H01J 49/0036 (2013.01); H01J 49/165 (2013.01); H01J 49/0004 (2013.01); H01J 49/142 (2013.01);
Abstract

The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a tissue sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis. Due to the use of a liquid phase that does not destroy native tissue morphology during analysis, a subsequent staining technique can be performed on the tissue sample and an overlaid image can be produced of a mass spectral image and a staining image.


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