The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2021

Filed:

Feb. 24, 2016
Applicants:

Adaptive Biotechnologies Corporation, Seattle, WA (US);

Fred Hutchinson Cancer Research Center, Seattle, WA (US);

Inventors:

Ryan O. Emerson, Seattle, WA (US);

Harlan S. Robins, Seattle, WA (US);

Mark Rieder, Seattle, WA (US);

William Dewitt, III, Seattle, WA (US);

Christopher Carlson, Seattle, WA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6881 (2018.01); C12Q 1/68 (2018.01); C12Q 1/70 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6881 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/70 (2013.01); C12Q 1/6869 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/172 (2013.01);
Abstract

Methods are provided for predicting a subject's infection status using high-throughput T cell receptor sequencing to match the subject's TCR repertoire to a known set of disease-associated T cell receptor sequences. The methods of the present invention may be used to predict the status of several infectious agents in a single sample from a subject. Methods are also provided for predicting a subject's HLA status using high-throughput immune receptor sequencing.


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