The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2021
Filed:
Sep. 17, 2019
Applicant:
University of Massachusetts, Boston, MA (US);
Inventors:
Christian Mueller, Concord, MA (US);
Neil Aronin, Newtonville, MA (US);
Edith L. Pfister, Boxborough, MA (US);
Assignee:
University of Massachusetts, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 7/00 (2006.01); A61P 25/28 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61P 25/28 (2018.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12N 2310/141 (2013.01); C12N 2310/3519 (2013.01); C12N 2330/51 (2013.01); C12N 2750/14121 (2013.01); C12N 2750/14141 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14171 (2013.01);
Abstract
Aspects of the disclosure relate to compositions and methods useful for treating Huntington's disease. In some embodiments, the disclosure provides interfering nucleic acids (e.g., artificial miRNAs) targeting the huntingtin gene (HTT) and methods of treating Huntington's disease using the same.