The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2021

Filed:

Apr. 11, 2019
Applicants:

Salubris Biotherapeutics, Inc., Gaithersburg, MD (US);

Genekey Biotech (Chengdu) Co., Ltd., Chengdu, CN;

Inventors:

John Li, Reston, VA (US);

Shengwei Li, Chengdu, CN;

Dixiang Luo, Chengdu, CN;

Yiran Wu, Chengdu, CN;

Ming Zhou, Shandong, CN;

Xiaolei Zhuang, North Potomac, MD (US);

Liang Hua, Zigong, CN;

Pengyi Luo, Chengdu, CN;

Yang Wang, Sichuan, CN;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/475 (2006.01); C12N 15/90 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4756 (2013.01); C12N 15/907 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present invention relates to a recombinant fusion protein comprising a fragment of the cardioprotective protein neuregulin-1 (NRG-1) fused to a monoclonal antibody (mAb) backbone and to a method of treating a disease or condition in a subject in need thereof comprising administering a therapeutically effective amount of the recombinant fusion protein or the pharmaceutical composition comprising the recombinant fusion protein disclosed herein.


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