The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2021

Filed:

Nov. 27, 2017
Applicant:

Xavier University of Louisiana, New Orleans, LA (US);

Inventors:

Guangdi Wang, New Orleans, LA (US);

Shilong Zheng, New Orleans, LA (US);

Jiawang Liu, New Orleans, LA (US);

Qiu Zhong, New Orleans, LA (US);

Shanchun Guo, New Orleans, LA (US);

Assignee:

Xavier University of Louisiana, New Orleans, LA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); A61P 35/00 (2018.01);
Abstract

The present disclosure relates to boronic derivatives of hydroxamate compounds, methods for making the same, methods for use as a monotherapy or in combination with one or more other therapeutic agents, for treatment of proliferative diseases such as cancer. The present disclosure also teaches the utilization of said boronic derivatives of hydroxamates as epigenetic therapy medications with enhanced bioavailability, lower-toxicity, and longer-lasting efficacy.


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