The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2021
Filed:
Oct. 07, 2019
Applicant:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Inventors:
Shaomeng Wang, Superior Township, MI (US);
Angelo Aguilar, Ann Arbor, MI (US);
Yangbing Li, Ann Arbor, MI (US);
Jiuling Yang, Ypsilanti, MI (US);
Donna McEachern, Ann Arbor, MI (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/10 (2006.01);
U.S. Cl.
CPC ...
C07D 487/10 (2013.01);
Abstract
The present disclosure provides compounds represented by Formula I: wherein R, R, R, R, R, R, R, A, L, X, Y, and Z are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I for use to treat cancer or any other disease, condition, or disorder that is responsive to degradation of MDM2 protein.