The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2021

Filed:

Mar. 06, 2017
Applicant:

Ohio State Innovation Foundation, Columbus, OH (US);

Inventors:

Gireesh Rajashekara, Columbus, OH (US);

Ulyana Munoz Acuna, Columbus, OH (US);

Janet Antwi, Columbus, OH (US);

Esperanza Carcache de Blanco, Columbus, OH (US);

James Fuchs, Columbus, OH (US);

Anand Kumar, Columbus, OH (US);

Corey Nislow, Columbus, OH (US);

Melvin Pascall, Columbus, OH (US);

Zilu Wan, Columbus, OH (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01); C07D 333/34 (2006.01); A01N 43/10 (2006.01); A01N 43/40 (2006.01); A61P 31/04 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); A01N 43/10 (2013.01); A01N 43/40 (2013.01); A61P 31/04 (2018.01); C07D 333/34 (2013.01); A61K 9/0014 (2013.01); A61K 9/0053 (2013.01); A61K 9/70 (2013.01);
Abstract

Compounds and compositions of matter are provided that are small molecule antimicrobials. The compounds are selected from JH-144, TH-04 or TH-08 or combinations thereof. Compositions of matter are provided which in an embodiment may comprise a carrier, and in further embodiments may comprise a pharmaceutically acceptable excipient, film, biofilm or edible film. Methods of use are provided in which the composition may be administered to a subject in need thereof, and in an embodiment where the subject has a bacterial infection. Other embodiments provide the composition may be contacted with surface to eliminate or reduce bacteria.


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