The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2021

Filed:

Jul. 17, 2019
Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Richard T. Lewis, Missouri City, TX (US);

Matthew Hamilton, Missouri City, TX (US);

Philip Jones, Houston, TX (US);

Alessia Petrocchi, Houston, TX (US);

Naphtali Reyna, Arlington, TX (US);

Timothy McAfoos, Pearland, TX (US);

Jason Bryant Cross, Pearland, TX (US);

Michael J. Soth, Sugar Land, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/233 (2006.01); C07D 401/14 (2006.01); A61K 31/47 (2006.01); C07D 235/08 (2006.01); A61K 31/4184 (2006.01); C07D 401/12 (2006.01); A61K 31/4709 (2006.01); A61K 31/4439 (2006.01); C07D 403/12 (2006.01); C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61K 31/506 (2006.01); C07D 413/12 (2006.01); A61K 31/423 (2006.01); C07D 417/12 (2006.01); A61K 31/428 (2006.01); A61K 31/497 (2006.01); A61K 31/501 (2006.01); A61K 31/433 (2006.01); A61K 31/4245 (2006.01); C07D 487/04 (2006.01); A61K 31/519 (2006.01); C07D 405/14 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 215/233 (2013.01); A61K 31/4184 (2013.01); A61K 31/423 (2013.01); A61K 31/428 (2013.01); A61K 31/4245 (2013.01); A61K 31/433 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/497 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); C07D 235/08 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention relates to bicyclic compounds and compositions and methods which may be useful as inhibitors of IDO1, IDO2, and TDO for the treatment or prevention of diseases such as cancer.


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