The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2021

Filed:

Feb. 26, 2018
Applicants:

Deirdre Meldrum, Phoenix, AZ (US);

Laimonas Kelbauskas, Gilbert, AZ (US);

Yanqing Tian, Tempe, AZ (US);

Honor Glenn, Mesa, AZ (US);

Clifford Anderson, Tempe, AZ (US);

Kristen Lee, Mesa, AZ (US);

Ganquan Song, Mesa, AZ (US);

Liqiang Zhang, Chandler, AZ (US);

Jeff Houkal, Los Angeles, CA (US);

Fengyu Su, Tempe, AZ (US);

Benjamin Ueberroth, Scottsdale, AZ (US);

Jacob Messner, Scottsdale, AZ (US);

Hong Wang, Scottsdale, AZ (US);

Kimberly Bussey, Scottsdale, AZ (US);

Inventors:

Deirdre Meldrum, Phoenix, AZ (US);

Laimonas Kelbauskas, Gilbert, AZ (US);

Yanqing Tian, Tempe, AZ (US);

Honor Glenn, Mesa, AZ (US);

Clifford Anderson, Tempe, AZ (US);

Kristen Lee, Mesa, AZ (US);

Ganquan Song, Mesa, AZ (US);

Liqiang Zhang, Chandler, AZ (US);

Jeff Houkal, Los Angeles, CA (US);

Fengyu Su, Tempe, AZ (US);

Benjamin Ueberroth, Scottsdale, AZ (US);

Jacob Messner, Scottsdale, AZ (US);

Hong Wang, Scottsdale, AZ (US);

Kimberly Bussey, Scottsdale, AZ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 15/14 (2006.01); G02B 21/34 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
B01L 3/50851 (2013.01); B01L 3/50853 (2013.01); G01N 15/1484 (2013.01); G02B 21/34 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/046 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0822 (2013.01); B01L 2400/0475 (2013.01); G01N 2015/1006 (2013.01);
Abstract

An integrated technological platform enabling real-time quantitative multiparameter metabolic profiling, utilizing either or both of extra and intracellular optical sensors, individually or simultaneously. A scalable embedded micropocket array structure, generally fabricated on fused silica substrates, facilitates the integration of multiple, spatially separated extracellular sensors for multiparameter analysis in a container formed with the use of an activation mechanism forming part of a device configured to hold the container during the measurements. The creation of hermetically sealed microchambers is carried out with a pneumatically and/or mechanically and/or electromechanically driven device that is 'floating' within the holding device and that is optionally equipped with a vacuum/suction mechanism to hold a component of the container at its surface.


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