The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2021

Filed:

Jun. 10, 2019
Applicants:

Massachusetts Eye & Ear Infirmary, Boston, MA (US);

Ucl Business Ltd., London, GB;

The Govt. of the Usa, As Represented BY the Secy., Dept. of Health and Human Services, Bethesda, MD (US);

Inventors:

Michael A. Sandberg, Reading, MA (US);

Basil Pawlyk, Hampton Falls, NH (US);

Alan Finlay Wright, Edinburgh, GB;

Xinhua Shu, Glasgow, GB;

Tiansen Li, Clarksburg, MD (US);

Robin Ali, London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07K 14/47 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/005 (2013.01); A61K 9/0048 (2013.01); C07K 14/4702 (2013.01); C12N 2750/14143 (2013.01);
Abstract

Methods for treating a human subject who has X-linked Retinitis Pigmentosa (XLRP) or another clinically-defined ophthalmological condition due to a loss-of-function mutation in the gene encoding the retinitis pigmentosa GTPase regulator (RPGR) protein, the method comprising administering to the subject a nucleic acid comprising an adeno-associated viral vector comprising an abbreviated human RPGR cDNA.


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