The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2021
Filed:
Jun. 08, 2017
Applicants:
Queen's University AT Kingston, Kingston, CA;
Kingston Health Sciences Centre, Kingston, CA;
Inventor:
Jagdeep Singh Walia, Kingston, CA;
Assignees:
Queen's University at Kingston, Kingston, CA;
Kingston Health Sciences Centre, Kingston, CA;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/86 (2006.01); C12N 9/24 (2006.01); A61K 31/405 (2006.01); A61K 31/505 (2006.01); A61K 38/47 (2006.01); A61K 31/27 (2006.01);
U.S. Cl.
CPC ...
A61K 48/00 (2013.01); A61K 31/27 (2013.01); A61K 31/405 (2013.01); A61K 31/505 (2013.01); A61K 38/47 (2013.01); C12N 9/2402 (2013.01); C12N 15/86 (2013.01); C12Y 302/01052 (2013.01); C12N 2750/14143 (2013.01);
Abstract
Disclosed are novel gene therapy constructs containing both HEXA and HEXB genes to treat GM2 gangliosidoses, including Sandhoff disease and Tay-Sach's disease. Also described are co-treatments using chaperone and anti-inflammatory agents to enhance the effects of gene therapy.