The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2021
Filed:
Apr. 04, 2017
International Business Machines Corporation, Armonk, NY (US);
Agency for Science, Technology and Research (Astar), Singapore, SG;
Dylan J. Boday, Austin, TX (US);
Jeannette M. Garcia, San Leandro, CA (US);
James L. Hedrick, Pleasanton, CA (US);
Nathaniel H. Park, San Jose, CA (US);
Rudy J. Wojtecki, San Jose, CA (US);
Yang Chuan, The Nanos, SG;
Ashlynn Lee, The Nanos, SG;
Zhen Chang Liang, The Nanos, SG;
Shaoqiong Liu, The Nanos, SG;
Yi Yan Yang, The Nanos, SG;
International Business Machines Corporation, Armonk, NY (US);
Abstract
A stimulus-responsive micellar carrier, methods that may be associated with making a stimulus-responsive micellar carrier, and methods that may be associated with using a stimulus-responsive micellar carrier are disclosed. The stimulus-responsive micellar carrier comprises a cargo molecule, and a linear block copolymer having a hydrophilic block connected to a hydrophobic block by a stimulus-responsive junction moiety. The micellar carrier can be supplied to a patient body for therapeutic purposes, such as the treatment of cancerous tissue. A method of preparing or obtaining a stimulus-responsive micellar carrier may include preparing a polyethylene glycol material having an acetal end group and then preparing a block copolymer by forming a reaction mixture including the polyethylene glycol material, a cyclic carbonate monomer, and a base.