The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11045525 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 29, 2021

Filed:

Jul. 02, 2018
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Antonio Iavarone, New York, NY (US);

Anna Lasorella, New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/45 (2006.01); A61K 38/44 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/45 (2013.01); A61K 38/44 (2013.01); A61P 35/00 (2018.01); C12Y 114/11002 (2013.01); C12Y 207/12001 (2013.01); C12N 2510/00 (2013.01);
Abstract

The present disclosure provides, in one embodiment, a method of treating or preventing an ID2 protein-related disease in a patient at risk of developing or having such a disease by administering to the patient a composition in an amount and for a time sufficient to increase degradation of HIFα in a cell affected by the ID2 protein-related disease in the patent and/or to decrease half-life of HIFα in the cell affected by the ID2 protein-related disease in the patient, as compared to an untreated cell affected by the ID2 protein-related disease.


Find Patent Forward Citations

Iavarone, Antonio. (2021). Compositions and methods for regulating activity of inhibitor of dna binding-2 (id2) protein and for treating id protein-related diseases (U.S. Patent No. 11045525). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11045525

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