The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2021
Filed:
Feb. 03, 2015
Pharmaceutical composition comprising diamino heterocyclic carboxamide compound as active ingredient
Applicant:
Astellas Pharma Inc., Chuo-ku, JP;
Inventors:
Assignee:
ASTELLAS PHARMA INC., Chuo-ku, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/517 (2006.01); A61K 45/06 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/497 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01);
Abstract
A pharmaceutical composition is suitable for treating AXL-related cancer. The cancer can be cancer with high expression of AXL. The cancer can also be cancer which has acquired resistance by the activation of AXL against therapy with an anticancer agent. Specific diamino heterocyclic carboxamide compounds have an AXL inhibitory action, and pharmaceutical compositions comprising these compounds as an active ingredient have a therapeutic effect on AXL-related cancer. This AXL-related cancer can be cancer with high expression of AXL and/or cancer which has acquired resistance by the activation of AXL against therapy with an anticancer agent.