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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11045457 B1

PDFFull Text
Date of Patent:
Jun. 29, 2021

Filed:

Feb. 28, 2019

Piperidinyl-3-(aryloxy)propanamides and propanoates

Applicants:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Zacharia Cheruvallath, San Diego, CA (US);

Jason Green, San Diego, CA (US);

Ben Johnson, San Diego, CA (US);

Kristin Schleicher, San Diego, CA (US);

Huikai Sun, San Diego, CA (US);

Mingnam Tang, San Diego, CA (US);

Inventors:

Zacharia Cheruvallath, San Diego, CA (US);

Jason Green, San Diego, CA (US);

Ben Johnson, San Diego, CA (US);

Kristin Schleicher, San Diego, CA (US);

Huikai Sun, San Diego, CA (US);

Mingnam Tang, San Diego, CA (US);

Assignee:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Attorney:

Matthew J. Russo

Primary Examiner:

Deepak R Rao

Int. Cl.
CPC ...
C07D 207/14 (2006.01); A61K 31/4439 (2006.01); A61K 31/40 (2006.01); A61K 31/4355 (2006.01); A61K 31/438 (2006.01); A61K 31/4468 (2006.01); A61K 31/4545 (2006.01); A61K 31/497 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); C07D 211/58 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 31/40 (2013.01); A61K 31/438 (2013.01); A61K 31/4355 (2013.01); A61K 31/4468 (2013.01); A61K 31/4545 (2013.01); A61K 31/497 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); C07D 207/14 (2013.01); C07D 211/58 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 491/048 (2013.01);
Abstract

Disclosed are compounds of Formula 1, stereoisomers thereof, and pharmaceutically acceptable salts thereof, wherein L, r, s, R, R, R, R, R, R, R, X, X, X, X, X, and Xare defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating diseases, disorders, and conditions associated with SSTR4.

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