The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2021

Filed:

Dec. 28, 2016
Applicants:

Johannes Gutenberg-universität Mainz, Mainz, DE;

03;universitätsmedizin Der Johannes Gutenberg-universitat Mainz, Mainz, DE;

Inventors:

Markus Möhler, Mainz, DE;

Annett Maderer, Griesheim, DE;

Gerd Dannhardt, Mainz, DE;

Christopher Ganser, Mainz, DE;

Eva Lauermann, Mainz, DE;

René Mönnikes, Mainz, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 31/4025 (2006.01); A61P 35/00 (2006.01); A61K 31/4745 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4025 (2013.01); A61K 31/4745 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention relates to 3-(5-fluoroindolyl)-4-arylmaleimide compounds and pharmaceutical compositions containing them. The compounds of the present invention are protein kinases (GSK-3beta, VEGFR-2 and FLT-3) with antineoplastic activity. They can therefore be used for the treatment or prevention of tumors, in particular solid tumors.


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