The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2021

Filed:

Mar. 30, 2016
Applicants:

Biontech Rna Pharmaceuticals Gmbh, Mainz, DE;

Tron-translationale Onkologie an Der Universitatsmedizin Der Johannes Gutenberg-universitat Mainz Ggmbh, Mainz, DE;

Inventors:

Hossam Hefesha, Wiesbaden, DE;

Ugur Sahin, Mainz, DE;

Heinrich Haas, Mainz, DE;

Sebastian Kreiter, Mainz, DE;

Yves Hüsemann, Wiesbaden, DE;

Mustafa Diken, Mainz, DE;

Kerstin Walzer, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/107 (2006.01); A61K 9/127 (2006.01); A61K 48/00 (2006.01); A61K 31/675 (2006.01); A61K 31/7105 (2006.01); A61K 9/00 (2006.01); A61K 31/663 (2006.01); A61K 45/06 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01); A61K 47/18 (2017.01); A61K 47/24 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1075 (2013.01); A61K 9/0019 (2013.01); A61K 9/1272 (2013.01); A61K 31/663 (2013.01); A61K 31/675 (2013.01); A61K 31/7105 (2013.01); A61K 39/0011 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); A61K 47/186 (2013.01); A61K 47/24 (2013.01); A61K 48/00 (2013.01); A61P 35/00 (2018.01); A61K 2039/54 (2013.01);
Abstract

The present invention relates to lipid particles comprising at least one cationic lipid, at least one water-soluble therapeutically effective compound and RNA. Further, the present invention relates to a pharmaceutical composition comprising such particles. Said pharmaceutical composition is useful for inducing an immune response. It is also useful in a prophylactic and/or therapeutic treatment of a disease involving an antigen. Furthermore, the present invention relates to a method for producing the particles.


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