The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2021

Filed:

Feb. 06, 2018
Applicant:

Tata Consultancy Services Limited, Mumbai, IN;

Inventors:

Venkataramana Runkana, Pune, IN;

Beena Rai, Pune, IN;

Aditya Pareek, Pune, IN;

Balarama Sridhar Dwadasi, Pune, IN;

Rakesh Gupta, Pune, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06F 17/10 (2006.01); G16C 20/10 (2019.01); G16C 10/00 (2019.01); G16C 20/50 (2019.01); G16C 20/30 (2019.01); G06F 111/10 (2020.01);
U.S. Cl.
CPC ...
G16C 20/10 (2019.02); G16C 10/00 (2019.02); G16C 20/50 (2019.02); G06F 2111/10 (2020.01); G16C 20/30 (2019.02);
Abstract

A system and method for design of polymeric carrier for controlled release of molecules is provided. The method includes receiving a plurality of input parameters of a polymeric carrier, a solvent, and molecules to be released from the polymeric carrier from a database and performing Molecular Dynamics (MD) simulations to estimate thermodynamic and transport properties of the polymeric carrier, the solvent and the molecules to be released using on one or more input parameters from the plurality of input parameters. Based on the estimated thermodynamic and transport properties, swelling and degradation kinetics of the polymeric carrier and release kinetics of the molecules to be released from the polymeric carrier is estimated and generating a proposed formulation based on difference between estimated released kinetics and the targeted release kinetics of the molecules.


Find Patent Forward Citations

Loading…