The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2021

Filed:

Jul. 21, 2017
Applicant:

Retinal Solutions Llc, Ann Arbor, MI (US);

Inventors:

Kimberly Drenser, Novi, MI (US);

Michael T. Trese, Novi, MI (US);

Antonio Capone, Novi, MI (US);

Assignee:

RETINAL SOLUTIONS LLC, Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/483 (2006.01); G01N 33/49 (2006.01); A61K 38/00 (2006.01); G01N 33/68 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
G01N 33/689 (2013.01); A61K 38/1709 (2013.01); G01N 2800/368 (2013.01); G01N 2800/52 (2013.01);
Abstract

A method for determining the necessity of a pre-term birth treatment is provided based on obtaining a biological sample from a subject. The biological sample is analyzed for the presence of (P33S;P168S) Frizzled4 (Fzd4) gene variation. The subject or a fetus thereof is then treated for a proclivity to pre-term birth. The Fzd4 protein itself can also be analyzed for the (P33S;P168S) Fzd4 mutation.


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