The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2021

Filed:

May. 17, 2017
Applicants:

Genecentric Therapeutics, Inc., Research Triangle Park, NC (US);

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Hawazin Faruki, Durham, NC (US);

Myla Lai-Goldman, Durham, NC (US);

Greg Mayhew, Durham, NC (US);

Jonathan Serody, Duham, NC (US);

Charles Perou, Carrboro, NC (US);

David Neil Hayes, Chapel Hill, NC (US);

Assignees:

GeneCentric Therapeutics, Inc., Research Triangle Park, NC (US);

The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G16H 50/30 (2018.01); G16B 40/10 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); G16B 40/10 (2019.02); G16H 50/30 (2018.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Methods and compositions are provided for determining a subtype of lung squamous cell carcinoma (SQ) of an individual by detecting the expression level of at least one classifier biomarker selected from a group of gene signatures for lung squamous cell carcinoma. Also provided herein are methods and compositions for determining the response of an individual with a squamous cell carcinoma subtype to a therapy such as immunotherapy.


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