The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2021
Filed:
Dec. 06, 2018
Applicants:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Idenix Pharmaceuticals Llc, Cambridge, MA (US);
Inventors:
Francois-Rene Alexandre, Montpellier, FR;
Rachid Rahali, Saint Laurent des Arbres, FR;
Izzat Raheem, Doylestown, PA (US);
Christophe Parsy, Jacou, FR;
Assignees:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Idenix Pharmaceuticals LLC, Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/40 (2006.01); C07D 473/32 (2006.01); C07D 239/47 (2006.01); C07D 239/54 (2006.01); A61K 31/675 (2006.01); A61K 31/7072 (2006.01); A61K 31/522 (2006.01); A61K 31/513 (2006.01); C07F 9/6561 (2006.01); A61K 31/52 (2006.01); C07F 9/6512 (2006.01);
U.S. Cl.
CPC ...
C07D 473/40 (2013.01); A61K 31/513 (2013.01); A61K 31/52 (2013.01); A61K 31/522 (2013.01); A61K 31/675 (2013.01); A61K 31/7072 (2013.01); C07D 239/47 (2013.01); C07D 239/54 (2013.01); C07D 473/32 (2013.01); C07F 9/6512 (2013.01); C07F 9/6561 (2013.01); C07F 9/65616 (2013.01);
Abstract
The present invention is directed carbocyclic nucleoside reverse transcriptase inhibitors compounds of Formula I and their use in the inhibition of HIV reverse transcriptase, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS and/or ARC.