The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2021

Filed:

Jul. 20, 2018
Applicants:

The Research Foundation for the State University of New York, Albany, NY (US);

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Clinton Rubin, Port Jefferson, NY (US);

Janet Rubin, Chapel Hill, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61N 1/05 (2006.01); A61N 2/02 (2006.01); A61M 5/00 (2006.01); C12N 13/00 (2006.01); A61M 31/00 (2006.01); A61N 2/00 (2006.01); A61N 5/06 (2006.01); A61N 1/32 (2006.01);
U.S. Cl.
CPC ...
A61N 2/02 (2013.01); A61M 5/00 (2013.01); A61N 1/05 (2013.01); C12N 13/00 (2013.01); A61M 31/002 (2013.01); A61N 1/326 (2013.01); A61N 2/00 (2013.01); A61N 5/062 (2013.01);
Abstract

The present invention relates to compositions and methods configured to deliver a stimulus (e.g., a therapeutic agent or a therapeutically beneficial signal) to a cell, tissue, organ, or organism. The stimulus is applied at least twice, and the first and second applications are separated by a rest period in which no further stimulus is actively applied. The rest period is of a duration (e.g., about 1-6 hours) sufficient to provoke an enhanced response to the second stimulus.


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