The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2021
Filed:
Nov. 07, 2018
Applicant:
Caliper Life Sciences, Inc., Waltham, MA (US);
Inventors:
Assignee:
Caliper Life Sciences, Inc., Waltham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0052 (2013.01); A61K 49/0019 (2013.01); A61K 49/0058 (2013.01); A61K 49/0093 (2013.01);
Abstract
The disclosure features methods that include: administering to a subject a composition that includes particles, where each one of the particles features at least one targeting group that binds to a structural entity in the subject and at least one reacting group that reacts chemically with a reactive oxygen species in the subject, and where the particle emits luminescence when the reaction occurs; detecting the luminescence emission from the particles; and displaying an image of the subject showing locations of at least some reactive oxygen species in the subject based on the detected luminescence.