The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2021

Filed:

Aug. 06, 2015
Applicant:

Georgia State University Research Foundation, Inc., Atlanta, GA (US);

Inventor:

Didier Merlin, Decatur, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 35/00 (2006.01); A61K 38/06 (2006.01); C07K 5/00 (2006.01); A61K 45/06 (2006.01); A61K 38/05 (2006.01); G01N 33/574 (2006.01); C07K 5/068 (2006.01); C07K 5/09 (2006.01); C07K 5/062 (2006.01); C07K 5/078 (2006.01); A61K 31/197 (2006.01); A61K 31/655 (2006.01); A61P 1/04 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
A61K 38/06 (2013.01); A61K 31/197 (2013.01); A61K 31/655 (2013.01); A61K 38/05 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); A61P 1/04 (2018.01); A61P 35/00 (2018.01); C07K 5/06026 (2013.01); C07K 5/06052 (2013.01); C07K 5/06086 (2013.01); C07K 5/06165 (2013.01); C07K 5/0815 (2013.01); G01N 33/57419 (2013.01); G01N 2800/50 (2013.01);
Abstract

The present invention relates to methods of treating a patient who has colorectal cancer and to methods of reducing the likelihood that a patient will develop or experience a recurrence of colorectal cancer. The methods comprise a step of introducing, to the patient, an effective amount of an agent that targets an intestinal H-coupled di/tripeptide transporter (PepT1). Useful compositions including, for example, the tripeptide KPV, vectors encoding such peptides, and cells (e.g., bacterial cells) including them, are also within the scope of the present invention, as are kits including such compositions.


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