The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2021
Filed:
May. 10, 2019
Applicant:
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Inventors:
Rudolph L. Juliano, Chapel Hill, NC (US);
Silvia M. Kreda, Mebane, NC (US);
Ling Wang, Chapel Hill, NC (US);
Xin Ming, Chapel Hill, NC (US);
Lindsey Ingerman James, Chapel Hill, NC (US);
Ranathunga Arachchillage Yamuna Kumari Ariyarathna, Carrboro, NC (US);
Assignee:
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, Chapel Hill, NC (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7125 (2006.01); C12N 15/113 (2010.01); A61K 31/4184 (2006.01); A61K 31/4985 (2006.01); C07D 235/30 (2006.01); A61P 11/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7125 (2013.01); A61K 31/4184 (2013.01); A61K 31/4985 (2013.01); A61P 11/00 (2018.01); C07D 235/30 (2013.01); C12N 15/113 (2013.01); C12N 2310/314 (2013.01); C12N 2310/3233 (2013.01); C12N 2320/31 (2013.01); C12N 2320/33 (2013.01);
Abstract
This disclosure is directed to methods, compounds and compositions for delivering nucleic acids to a cell of interest. In particular, it provides salts that are particularly effective in delivering nucleic acids to cells in the lung for disorders such as cystic fibrosis (CF).