The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2021
Filed:
Mar. 21, 2018
Applicant:
Katholieke Universiteit Leuven, Leuven, BE;
Inventors:
Graciela Andrei, Leuven, BE;
Steven De Jonghe, Leuven, BE;
Elisabetta Groaz, Leuven, BE;
Piet Herdewijn, Heverlee, BE;
Min Luo, Leuven, BE;
Dominique Schols, Leuven, BE;
Robert Snoeck, Leuven, BE;
Assignee:
Katholieke Universiteit Leuven, Leuven, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/675 (2006.01); A61P 31/22 (2006.01); C07F 9/6584 (2006.01);
U.S. Cl.
CPC ...
A61K 31/675 (2013.01); A61P 31/22 (2018.01); C07F 9/6584 (2013.01);
Abstract
The present invention relates to novel phosphonoamidate prodrugs. The invention also relates to the use of these novel phosphonate-modified nucleosides to treat or prevent viral infections and their use to manufacture a medicine to treat or prevent viral infections, particularly infections with viruses such as the herpes simplex virus 1, herpes simplex virus 2, human cytomegalovirus, varicella zoster virus, vaccinia virus and adenovirus.