The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2021
Filed:
Jul. 26, 2019
Sumitomo Dainippon Pharma Oncology, Inc., Cambridge, MA (US);
Steven L. Warner, Sandy, UT (US);
David J. Bearss, Alpine, UT (US);
Adam Siddiqui-Jain, South Jordan, UT (US);
Clifford J. Whatcott, West Jordan, UT (US);
Jason Marc Foulks, Sandy, UT (US);
Stephen Patrick Anthony, Heber City, UT (US);
Paul Flynn, Citrus Heights, CA (US);
Yuji Fujiwara, Draper, UT (US);
Yuka Arikawa, Minoh, JP;
SUMITOMO DAINIPPON PHARMA ONCOLOGY, INC., Cambridge, MA (US);
Abstract
Methods for treating a disease in a subject in need thereof by administering an ACVR1 inhibitor having the following formula (I) are disclosed: including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R, R, R, and Rare as defined herein. Subjects that may benefit from treatment may have mutations in their ACVR1 gene. Various diseases may be treated using the described methods, including cancers (e.g., diffuse intrinsic pontine glioma (DIPG)) and genetic disorders (e.g., fibrodysplasia ossificans progressiva (FOP)).